AFA formulas provide potent antioxidant benefits and effective exfoliation gentle enough for all skin types

Sold in over 30 countries, AFA is available exclusively through dermatologists, plastic surgeons, cosmetic physicians and licensed medical estheticians. AFA is formulated with a blend of amino-based filaggrin antioxidants to work synergistically with the skin’s other natural moisture factors (NMFs). Filaggrin is a protein of the epidermis which metabolizes into amino acids and acts as one of the primary agents for retaining moisture in the skin. Through this high-effective formula, AFA products exfoliate, repair and refine skin with minimal irritation, making them an ideal solution for patients with all skin types who are experiencing acne, general signs of aging or even sun damage.

None of the skin care products in the AFA line are tested on animals.

What is the heart of AFA?


AFA: Amino-based Filaggrin Antioxidants

The AFA skin care line is based on the amino-based filaggrin antioxidants generally occurring as part of the natural moisture factors (NMF) of human skin, which play a vital role in maintaining healthy barrier function and helping skin to be more healthy and youthful.

AFA products are formulated with highly-potent, stabilized antioxidants and powerful exfoliants which, belying their efficacy, produce little to no irritation unlike AHAs, glycolic acids, and other alpha hydroxy acids. AFA products are extremely effective in diminishing the signs of aging, sun damage and hyperpigmentation.

Extraordinary AFA Results:
  • Improved skin texture
  • Diminished hyperpigmentation and signs of sun damage
  • Refinement in appearance of enlarged pores
  • Minimization of acne breakouts and rosacea
  • Improvement in fine lines and wrinkles
Unique Benefits of AFA:
  • Improved barrier function
  • Increased moisture retention
  • Highly-potent, stabilized antioxidants
  • Clinically-significant results with little to no irritation

Created by:


Dr. Marvin E. Klein

Dr. Marvin E. Klein, a board certified dermatologist, created and developed AFA (then called AFAs). An entrepreneur and avid researcher with a passion for biochemistry, Dr. Klein founded exCel Manufacturing, Inc. and then searched for a formula that provided significant anti-aging benefits without the dryness and irritation commonly associated with other AHA products. From that research, he discovered a way to further acidify the same amino acids that are present in the epidermis of the human skin that are recognized as a part of the natural moisture factors (NMFs) of the skin. From that discovery, he created the cosmeceutical compounds that became the heart of AFA – amino acid filaggrin-based antioxidants.

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Dr. Joel Schlessinger, MD

A board-certified dermatologist and cosmetic surgeon, Dr. Joel Schlessinger was a long-time friend to Dr. Marvin E. Klein and has been intimately involved with the AFA line since the early days when it was called AFAs and distributed by exCel Manufacturing, Inc.. Dr. Schlessinger has known the principals of the company since 1993 and through his relationship with Dr. Klein, has been substantially involved in the scientific exploration and testing of the products. For the last 25 years Dr. Schlessinger has been an advocate for the brand through international lectures, published works and to the patients in his very own practice located in Omaha, NE. In the interest of keeping AFA available to patients around the globe, Dr. Schlessinger purchased exCel Manufacturing, Inc. in 2017 to continue the work of his colleague and friend, the late Dr. Klein.

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Do your current patient offerings provide results like these? If not, try AFA.

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